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SH3BP4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 17691-1-AP-20UL
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Description
SH3BP4 was initially isolated as a novel cDNA using differential display analysis using cultured human corneal fibroblasts. The protein contains three Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. SH3BP4 has been shown to interact with specific endocytic proteins such as clathrin, dynamin, and the transferrin receptor (TfR) and localizes to TfR-containing coated pits and vesicles. It is thought to be involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of TfR. At least two isoforms of SH3BP4 are known to exist.Specifications
| SH3BP4 | |
| Polyclonal | |
| Unconjugated | |
| SH3BP4 | |
| BOG25, EH binding protein 10, EHB10, SH3 domain binding protein 4, SH3BP4, TTP | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 23677, 64634, 98402 | |
| -20°C | |
| Liquid |
| Immunofluorescence, Western Blot, Immunoprecipitation, Immunocytochemistry | |
| 0.18 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q921I6, Q9JJS5, Q9P0V3 | |
| Sh3bp4 | |
| SH3BP4 Fusion Protein Ag11847 | |
| 20 μL | |
| Primary | |
| Mouse, Human, Rat | |
| Antibody | |
| IgG |
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