missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ Human FBXL20 Synthetic Peptide
Synthetic Peptide
Brand: Invitrogen™ PEP0606
This item is not returnable.
View return policy
Description
SCRAPPER Synthetic Peptide, PEP-0606, from Invitrogen.
Members of the F-box protein family, such as Scrapper, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. Scrapper is selectively expressed in the brain, broadly expressed within the mouse CNS and is abundant at presynaptic membrane. Scrapper has orthologs in C. elegans, D. melanogaster, and mammals which suggests that it might function as an important membrane-localized E3 ligase in various species. Scrapper is a major presynaptic E3 ubiquitin ligase that acts through RIM1a via degradation and the ubiquitin-proteasome-system (UPS) pathway to critically regulate synaptic transmission. This identifies protein degradation as a mechanism for holding synaptic communication in check.
Specifications
| 84961 | |
| purified | |
| Human FBXL20 | |
| -20°C | |
| Liquid | |
| Blocking Assay, Control | |
| No | |
| Peptide | |
| RUO - research use only |
| Human | |
| Q96IG2 | |
| 200 μg/mL | |
| Synthetic Peptide | |
| PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 | |
| FBXL20 | |
| 0.02% sodium azide | |
| 50 μg | |
| PBS |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction