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Rubicon Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
1645.54 SEK - 4652.90 SEK
Specifications
| Antigen | Rubicon |
|---|---|
| Concentration | 0.47 mg/mL |
| Applications | Western Blot, Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
16851035
|
Proteintech
21444-1-AP-20UL |
20 μL |
1645.54 SEK
20µL |
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|
16841035
|
Proteintech
21444-1-AP-150UL |
150 μL |
4652.90 SEK
150µL |
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Description
Two Beclin-1-interacting proteins, the run domain Beclin-1 interacting and cysteine-rich containing protein (Rubicon) and ATG14L, reciprocally regulate autophagy at different stages. Knockdown of Rubicon caused enhancement of autophagy while that of ATG14L caused a defect in autophagosome formation. Rubicon functions as part of a Beclin-1-PIK3C3-containing autophagy complex and is also an essential, positive regulator of the NAPDH oxidase complex. Upon microbial infection or TLR2 activation, Rubicon interacts with the CYBA subunit of the NAPDH oxidase complex, leading to a burst of reactive oxygen species and inflammatory cytokines.Specifications
| Rubicon | |
| Western Blot, Immunohistochemistry (Paraffin) | |
| Unconjugated | |
| Rabbit | |
| Rat, Human, Mouse | |
| Q80U62, Q92622 | |
| 100502698, 303885, 9711 | |
| Rubicon Fusion Protein Ag13715 | |
| Primary | |
| -20°C | |
| RUBCN |
| 0.47 mg/mL | |
| Polyclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Baron, KIAA0226, RUBCN, Rubicon | |
| Rubcn | |
| IgG | |
| Antigen Affinity Chromatography | |
| Antibody |
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