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MT1-MMP Rabbit anti-Human, Mouse, Rat, Zebrafish, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 14552-1-AP-20UL
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Description
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP′s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.Specifications
| MT1-MMP | |
| Polyclonal | |
| Unconjugated | |
| MMP14 | |
| Matrix metalloproteinase 14, MMP 14, MMP X1, MMP14, MT MMP 1, MT1 MMP, MT1MMP, MT1-MMP, MTMMP1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 17387, 373882, 4323, 81707 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunofluorescence, Western Blot | |
| 0.2 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P50281, P53690, Q10739 | |
| Mmp14, mmp14a | |
| MT1-MMP Fusion Protein Ag5965 | |
| 20 μL | |
| Primary | |
| Human, Mouse, Zebrafish, Rat | |
| Antibody | |
| IgG |
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