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Thermo Scientific™ GlycoLink™ Coupling Catalyst
Enhance aldehyde-hydrazide crosslinking efficiency for glycoprotein immobilization and conjugation with analine (CAS 62-53-3) and an optimized buffer system.
Brand: Thermo Scientific™ 88944
689.04 SEK valid until 2025-06-30
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This item is not returnable.
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Description
The Thermo Scientific™ GlycoLink Coupling Catalyst decreases reaction times and increases aldehyde-hydrazide coupling efficiency, resulting in greater than 90% coupling of glycoproteins in 4 hours.
The GlycoLink Coupling Catalyst is a two-component kit composed of aniline and sodium acetate buffer. The catalyst accelerates the coupling rate of hydrazide and alkoxyamine moieties with reactive aldehydes that have been generated by periodate-oxidation of cis-diols in glycoproteins. The GlycoLink Coupling Catalyst increases the coupling efficiency of these reactions, decreasing the molar excess amounts of labeling reagents that are required for conjugation reactions. The catalyst is also useful for increasing the binding efficiency of oxidized glycoproteins or other carbohydrate-containing molecules to hydrazide resins.
Highlights:
Optimized – catalyzes aldehyde-hydrazide and aldehyde-alkoxyamine conjugation reaction
Efficient – maximizes coupling efficiency and decreases required coupling reaction incubation time
Gentle – does not interfere with protein function and is easily removed by desalting or dialysis
Recommended for:
Labeling aldehyde-containing molecules with alkoxyamine-biotins; Labeling aldehyde-containing molecules with hydrazide-biotins; Increase coupling efficiency of aldehyde-containing molecules to hydrazide resin
Specifications
| Store at 4°C. | |
| Liquid | |
| Coupling Catalyst |
| GlycoLink™ | |
| 100 mL |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- GlycoLink Coupling Catalyst
Signal Word
- Danger
Hazard Category
- Acute toxicity Category 2
- Acute toxicity Category 3
- ACUTE AQUATIC Acute 1
- Carcinogenicity Category 2
- Serious eye damage/eye irritation Category 1
- Germ cell mutagenicity Category 2
- Skin sensitiser Category 1
- Specific target organ toxicity Category 1
Hazard Statement
- H251-Self-heating: may catch fire.
- H301-Toxic if swallowed.
- H311-Toxic in contact with skin.
- H317-May cause an allergic skin reaction.
- H318-Causes serious eye damage.
- H330-Fatal if inhaled.
- H341-Suspected of causing genetic defects.
- H372-Causes damage to organs.
- H400-Very toxic to aquatic life.
Precautionary Statement
- P201-Obtain special instructions before use.
- P260-Do not breathe dust/fume/gas/mist/vapours/spray.
- P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
- P302+P352-IF ON SKIN: Wash with plenty of water/soap.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Supplemental information
- MIXTURE LIST-Contains : Aniline
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Product Title
For Research Use Only. Not for use in diagnostic procedures.
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