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Dexamethasone, 96%, Thermo Scientific Chemicals
Dexamethasone, CAS# 50-02-2, is a synthetic adrenal corticosteroid that shows potent anti-inflammatory activity.
769.81 SEK - 3706.72 SEK
Chemical Identifiers
| CAS | 50-02-2 |
|---|---|
| Molecular Formula | C22H29FO5 |
| Molecular Weight (g/mol) | 392.47 |
| MDL Number | MFCD00064136 |
| InChI Key | UREBDLICKHMUKA-CXSFZGCWSA-N |
| Synonym | dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol |
| PubChem CID | 5743 |
| ChEBI | CHEBI:41879 |
| SMILES | C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO |
| Product Code | Brand | Quantity | Packaging | Price | Quantity & Availability | ||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Packaging | Price | Quantity & Availability | ||||
|
10053130
|
Thermo Scientific Acros
230302500 |
250 mg | Glass bottle |
769.81 SEK
250mg |
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|
10502631
|
Thermo Scientific Acros
230300010 |
1 g | Glass bottle |
1573.93 SEK
1g |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
|
10434225
|
Thermo Scientific Acros
230300050 |
5 g | Glass bottle |
3706.72 SEK
5g |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Beschreibung
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Information
• Dexamethasone is a synthetic adrenal glucocorticoid that modulates carbohydrate metabolism, inhibits adrenocorticotropic hormone secretion, and has pronounced anti-inflammatory activity
• Dexamethasone can bind to specific nuclear steroid receptors, inhibiting pro-inflammatory signals, promoting anti-inflammatory signals, and interfering with NF-kB activation and apoptotic pathways
Applications
• It can be used to study apoptosis, cell signaling pathways, and gene expression
• This compound also shows adrenergic, antiemetic, and antineoplastic activities
• It has been used as an important regulator of cellular proliferation and differentiation in vitro human cell cultures
• Dexamethasone has been applied in culture media to promote the differentiation of adipose-derived stem cells into osteogenic tissue
• It is used in in vitro stimulation of primary normal human bronchial epithelial cells (NHBE) and airway smooth muscle (ASM)
• This compound is used for its ability to regulate T cell survival, growth, and differentiation.
• It can also inhibit the induction of nitric oxide synthase.
Chemische Identifikatoren
| 50-02-2 | |
| 392.47 | |
| UREBDLICKHMUKA-CXSFZGCWSA-N | |
| 5743 | |
| C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO |
| C22H29FO5 | |
| MFCD00064136 | |
| dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol | |
| CHEBI:41879 |
Spezifikation
| 50-02-2 | |
| White | |
| Authentic | |
| C22H29FO5 | |
| 15, 2945 | |
| dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol | |
| 95% min. (on dried substance) | |
| C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO | |
| 392.47 | |
| CHEBI:41879 | |
| 96% | |
| Crystalline Powder |
| 255.0°C to 261.0°C | |
| 0.5% max. (105°C, 3 hrs) | |
| 96% | |
| MFCD00064136 | |
| + 75.00 | |
| Solubility in water: 10mg/100mL (25 c). Other solubilities: soluble in acetone,ethanol and chloroform | |
| UREBDLICKHMUKA-CXSFZGCWSA-N | |
| (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one | |
| 5743 | |
| 392.46 | |
| (HPLC) Passes test | |
| Dexamethasone |
Sicherheit und Handhabung
GHS H Statement:
Suspected of causing cancer.
GHS P Statement:
Use personal protective equipment as required.
WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.
GHS Signal Word: Warning
missing translation for 'einecsNumber' : 200-003-9
Produktidentifikator
Signalwort
Gefahrenkategorie
Gefahrenhinweis
Sicherheitshinweis
- Dexamethasone
Signalwort
- Warning
Gefahrenkategorie
- Carcinogenicity Category 2
Gefahrenhinweis
- H351-Suspected of causing cancer.
Sicherheitshinweis
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
RUO – Research Use Only
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