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Molecular Probes™ 7-Amino-4-Methylcoumarin, reference standard
7-Amino-4-methylcoumarin (AMC) can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates. | 175.2 g/mol
Brand: Molecular Probes™ A191
Description
7-Amino-4-methylcoumarin (AMC) can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates. The fluorescence spectra of AMC is not subject to variability due to pH-dependent protonation/deprotonation when assayed near or above physiological pH.
To make a concentrated stock solution of up to 10 mg/mL, dissolve in either acetone, high quality anhydrous DMSO or DMF. Store frozen, desiccated and protected from light.

Specifications
100 mg | |
175.2 | |
Room Temperature | |
Coumarin Dyes | |
351 nm |
7-Amino-4-Methylcoumarin | |
Store at room temperature and protect from light. | |
Methylcoumarin | |
430 nm |
Safety and Handling
- Warning
Hazard Category
- Skin corrosion/irritation Category 2
- Serious eye damage/eye irritation Category 2
- Specific target organ toxicity Category 3
Hazard Statement
- H315-Causes skin irritation.
- H319-Causes serious eye irritation.
- H335-May cause respiratory irritation.
Precautionary Statement
- P264-Wash hands thoroughly after handling.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
- P271-Use only outdoors or in a well-ventilated area.
- P302+P352-IF ON SKIN: Wash with plenty of water/.
- P332+P313-If skin irritation occurs: Get medical advice/attention.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P362+P364-Take off contaminated clothing and wash it before reuse.
- P337+P313-If eye irritation persists: Get medical advice/attention.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P403+P233-Store in a well-ventilated place. Keep container tightly closed.
- P501-Dispose of contents/container to .
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For Research Use Only. Not for use in diagnostic procedures.