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2,2,2-Trifluoroethanol, 99+%, Thermo Scientific Chemicals
CAS: 75-89-8 | C2H3F3O | 100.04 g/mol
538.00 SEK - 3535.00 SEK
Chemical Identifiers
CAS | 75-89-8 |
---|---|
Molecular Formula | C2H3F3O |
Molecular Weight (g/mol) | 100.04 |
MDL Number | MFCD00004672 |
InChI Key | RHQDFWAXVIIEBN-UHFFFAOYSA-N |
Synonym | trifluoroethanol, ethanol, 2,2,2-trifluoro, 2,2,2-trifluoroethan-1-ol, fluorinol 85, 2,2,2-trifluoroethyl alcohol, trifluoroethyl alcohol, trifluoro ethanol, tfe, perfluoro-1,1-dihydroethanol, tfetoh |
PubChem CID | 6409 |
ChEBI | CHEBI:42330 |
SMILES | OCC(F)(F)F |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
11499702
|
Thermo Scientific Alfa Aesar
A10788.18 |
50 g |
538.00 SEK
50g |
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11474130
|
Thermo Scientific Alfa Aesar
A10788.22 |
100 g |
920.00 SEK
100g |
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11484130
|
Thermo Scientific Alfa Aesar
A10788.36 |
500 g |
2525.00 SEK
500g |
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11489702
|
Thermo Scientific Alfa Aesar
A10788.0B |
1000 g |
3535.00 SEK
1000g |
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Description
Trifluoroethanol serves as a solvent and a raw material in organic chemistry and biology. TFE is a solvent of choice for hydrogen peroxide-mediated oxidations of sulfides. Trifluoroethanol acts as a protein denaturant. It is used in the manufacture of certain pharmaceuticals and drug substances. The drug fluromer, which is 2,2,2-trifluoro-1-vinyloxyethane, is the vinyl ether of trifluorethanol. It is an effective solvent for peptides and proteins, and used for NMR-based protein folding studies, and in the manufacture of nylon. As a source of the trifluoromethyl group, it is employed in several organic reactions, for example in Still-Gennari modification of Horner-Wadsworth-Emmons reaction (HWE) reaction.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
ApplicationsTrifluoroethanol serves as a solvent and a raw material in organic chemistry and biology. TFE is a solvent of choice for hydrogen peroxide-mediated oxidations of sulfides. Trifluoroethanol acts as a protein denaturant. It is used in the manufacture of certain pharmaceuticals and drug substances. The drug fluromer, which is 2,2,2-trifluoro-1-vinyloxyethane, is the vinyl ether of trifluorethanol. It is an effective solvent for peptides and proteins, and used for NMR-based protein folding studies, and in the manufacture of nylon. As a source of the trifluoromethyl group, it is employed in several organic reactions, for example in Still-Gennari modification of Horner-Wadsworth-Emmons reaction (HWE) reaction.
Solubility
Miscible with water, ethers, ketones, alcohols and chloroform.
Notes
Moisture sensitive.
Chemical Identifiers
75-89-8 | |
100.04 | |
RHQDFWAXVIIEBN-UHFFFAOYSA-N | |
6409 | |
OCC(F)(F)F |
C2H3F3O | |
MFCD00004672 | |
trifluoroethanol, ethanol, 2,2,2-trifluoro, 2,2,2-trifluoroethan-1-ol, fluorinol 85, 2,2,2-trifluoroethyl alcohol, trifluoroethyl alcohol, trifluoro ethanol, tfe, perfluoro-1,1-dihydroethanol, tfetoh | |
CHEBI:42330 |
Specifications
75-89-8 | |
1.391 | |
29°C (84°F) | |
CF3CH2OH | |
MFCD00004672 | |
1733203 | |
Miscible with water,ethers,ketones,alcohols and chloroform. | |
OCC(F)(F)F | |
100.04 | |
CHEBI:42330 | |
≥99% |
-44°C | |
74°C to 75°C | |
C2H3F3O | |
1.29 | |
UN1992 | |
trifluoroethanol, ethanol, 2,2,2-trifluoro, 2,2,2-trifluoroethan-1-ol, fluorinol 85, 2,2,2-trifluoroethyl alcohol, trifluoroethyl alcohol, trifluoro ethanol, tfe, perfluoro-1,1-dihydroethanol, tfetoh | |
RHQDFWAXVIIEBN-UHFFFAOYSA-N | |
2,2,2-trifluoroethan-1-ol | |
6409 | |
100.04 | |
2,2,2-Trifluoroethanol |
Safety and Handling
GHS H Statement
H301-H311-H318-H226-H332-H315-H335
Toxic if swallowed.
Toxic in contact with skin.
Causes serious eye damage.
Flammable liquid and vapor.
Harmful if inhaled.
Causes skin irritation.
May cause respiratory irritation.
P201-P202-P210-P233-P235-P240-P241-P242-P243-P260-P264b-P270-P271-P281-P301+P310-P303+P361+P353-P304+P340-P305+P351+P338-P308+P313-P310-P311-P330-P370+P378q-P501c
H226-H301+H331-H318-H360F-H373
missing translation for 'dotInformation' : Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: FLAMMABLE LIQUIDS, TOXIC, N.O.S.
missing translation for 'einecsNumber' : 200-913-6
missing translation for 'rtecsNumber' : KM5250000
missing translation for 'tsca' : Yes
Recommended Storage : Ambient temperatures
- 2,2,2-Trifluoroethanol
Signal Word
- Danger
Hazard Category
- Acute toxicity Category 3
- Serious eye damage/eye irritation Category 1
- Flammable liquid Category 3
- Reproductive toxicity Category 1B
- Specific target organ toxicity after repeated exposure Category 2
Hazard Statement
- H226-Flammable liquid and vapour.
- H301-Toxic if swallowed.
- H311-Toxic in contact with skin.
- H318-Causes serious eye damage.
- H360F-May damage fertility.
- H373-May cause damage to organs.
Precautionary Statement
- P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P302+P352-IF ON SKIN: Wash with plenty of water/soap.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P310-Immediately call a POISON CENTER/doctor/.
Supplemental information
- MIXTURE LIST-Contains : 2,2,2-Trifluoroethanol
RUO – Research Use Only
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