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1-(Trimethylsilyl)imidazole, 97%, Thermo Scientific Chemicals

CAS: 18156-74-6 | C6H12N2Si | 140.26 g/mol

268.00 SEK - 4020.00 SEK

Chemical Identifiers

CAS 18156-74-6
Molecular Formula C6H12N2Si
Molecular Weight (g/mol) 140.26
MDL Number MFCD00005280
InChI Key YKFRUJSEPGHZFJ-UHFFFAOYSA-N
Synonym n-trimethylsilyl imidazole, 1-trimethylsilyl imidazole, 1-trimethylsilyl-1h-imidazole, tsim, 1h-imidazole, 1-trimethylsilyl, n-trimethylsilylimidazole, trimethylsilyl imidazole, 1-trimethylsilylimidazole, n-trimethylsilyl imidazol, imidazole, 1-trimethylsilyl
PubChem CID 28925
ChEBI CHEBI:85063
IUPAC Name imidazol-1-yl(trimethyl)silane
SMILES C[Si](C)(C)N1C=CN=C1
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11488710
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Thermo Scientific Alfa Aesar
A12512.06
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Thermo Scientific Alfa Aesar
A12512.18
50 g
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A12512.22
100 g
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Description

Description

1-(Trimethylsilyl)imidazole acts as a silylating agent for alcohols, carbohydrates and 1,3-dicarbonyl compounds. It is a derivatization reagent used for selective silylation of hydroxyl groups and carboxylic acid without affecting the amino group. It employed as an intermediate for the synthesis of imidazole derivatives. It plays an essential role to synthesize polysubstituted chiral spirotetrahydropyrans. It is also used in the quantification of pintol after derivatization by gas chromatography/ mass spectrometry.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1-(Trimethylsilyl)imidazole acts as a silylating agent for alcohols, carbohydrates and 1,3-dicarbonyl compounds. It is a derivatization reagent used for selective silylation of hydroxyl groups and carboxylic acid without affecting the amino group. It employed as an intermediate for the synthesis of imidazole derivatives. It plays an essential role to synthesize polysubstituted chiral spirotetrahydropyrans. It is also used in the quantification of pintol after derivatization by gas chromatography/ mass spectrometry.

Solubility
Miscible with most common organic solvents. It decomposes in water.

Notes
Moisture and light sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents and strong acids.
Specifications

Chemical Identifiers

18156-74-6
140.26
YKFRUJSEPGHZFJ-UHFFFAOYSA-N
28925
imidazol-1-yl(trimethyl)silane
C6H12N2Si
MFCD00005280
n-trimethylsilyl imidazole, 1-trimethylsilyl imidazole, 1-trimethylsilyl-1h-imidazole, tsim, 1h-imidazole, 1-trimethylsilyl, n-trimethylsilylimidazole, trimethylsilyl imidazole, 1-trimethylsilylimidazole, n-trimethylsilyl imidazol, imidazole, 1-trimethylsilyl
CHEBI:85063
C[Si](C)(C)N1C=CN=C1

Specifications

18156-74-6
0.956
18°C (64°F)
C6H12N2Si
MFCD00005280
606148
n-trimethylsilyl imidazole, 1-trimethylsilyl imidazole, 1-trimethylsilyl-1h-imidazole, tsim, 1h-imidazole, 1-trimethylsilyl, n-trimethylsilylimidazole, trimethylsilyl imidazole, 1-trimethylsilylimidazole, n-trimethylsilyl imidazol, imidazole, 1-trimethylsilyl
YKFRUJSEPGHZFJ-UHFFFAOYSA-N
imidazol-1-yl(trimethyl)silane
28925
140.26
1-(Trimethylsilyl)imidazole
-42°C
212°C
Weak
1.4765
UN1993
Moisture sensitive
Miscible with most common organic solvents. It decomposes in water.
C[Si](C)(C)N1C=CN=C1
140.26
CHEBI:85063
97%
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Safety and Handling

Safety and Handling

GHS H Statement
H225-H315-H319-H335
Highly flammable liquid and vapour.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

P210-P233-P235-P240-P241-P242-P243-P261-P264b-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P332+P313-P363-P370+P378q-P501c

H225-H315-H319-H335

missing translation for 'dotInformation' : Transport Hazard Class: 3; Packing Group: II; Proper Shipping Name: FLAMMABLE LIQUIDS, N.O.S.

missing translation for 'einecsNumber' : 242-040-3

missing translation for 'rtecsNumber' : NI8700000

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

Product Identifier
  • 1-(Trimethylsilyl)imidazole

Signal Word
  • Danger

Hazard Category
  • Acute toxicity Category 4
  • LONG-TERM AQUATIC HAZARD Chronic 1
  • Serious eye damage/eye irritation Category 1
  • Flammable liquid Category 2
  • Reproductive toxicity Category 1B
  • Skin corrosion/irritation Category 1 C

Hazard Statement
  • H225-Highly flammable liquid and vapour.
  • H302-Harmful if swallowed.
  • H314-Causes severe skin burns and eye damage.
  • H318-Causes serious eye damage.
  • H360D-May damage the unborn child.
  • H410-Very toxic to aquatic life with long lasting effects.

Precautionary Statement
  • P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310-Immediately call a POISON CENTER/doctor/.

Supplemental information
  • MIXTURE LIST-Contains : 1-(Trimethylsilyl)imidazole

SDS
Documents

Documents

Product Certifications

RUO – Research Use Only

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